7802 Results
1

UC study examines role of metabolites in disease treatment

June 8, 2023

Each year, about 200,000 people in the United States are diagnosed with a bulge in the lower part of the aorta, the main artery in the body, called an abdominal aortic aneurysm (AAA). New research from the University of Cincinnati examines the role a particular metabolite plays in the development of AAA and could lead to the first treatment of the condition.

3

Research reveals insights into transplant rejection, new drug targets

June 28, 2023

Imagine a day when a urine test could inform a doctor precisely why a kidney transplant patient was experiencing organ rejection and suggest the best medication for specifically addressing the problem. That day took a leap closer to reality thanks to a set of single-cell analyses that have identified the most specific cellular signatures to date for kidney transplant rejection. The findings were published in the Journal of Clinical Investigation.

5

Widespread naloxone distribution not enough to impact overdose death rate

September 28, 2023

The highest ever number of opioid-related overdose deaths in the United States was recorded in 2020 at 68,630, a 68% increase in just two years. Naloxone is a medicine that can rapidly reverse an opioid overdose, but a new study out of the University of Cincinnati finds that widespread community distribution of naloxone through a take-home naloxone program did not significantly impact the median monthly opioid overdose rates.

7

U.S. News & World Report: PFAS chemicals tied to later puberty in girls

October 3, 2023

Research out of the University of Cincinnati shows that exposure to PFAs chemicals delays the onset of puberty in girls by an average of five to six months. The research was published in the journal PLOS One. U.S. News & World Report published a story on the study, featuring comments from lead researcher Susan Pinney, MD, of the Department of Environmental and Public Health Sciences.

8

UC research shows PFA exposure may delay girls’ puberty

September 26, 2023

Research from the University of Cincinnati shows that exposure to PFAS may delay the onset of puberty in girls. The research was published in the journal Environmental Health Perspectives. This study is the first longitudinal research that included the component of the role hormones play in the delay, according to Susan Pinney, PhD, of the Department of Environmental and Public Health Sciences in the UC College of Medicine and corresponding author of the study.

9

UC cocaine research disrupts traditional theory

November 15, 2023

For more than 50 years, the conventional wisdom in the field of cocaine self-administration research has been that people take cocaine based on the theory of the drug providing positive reinforcement to the user. New research out of UC shows that a pharmacological equation disproves that concept and could spark a major shift in that field of research.