NBC News: New Alzheimer's drug comes with steep price tag

UC expert says doctors, patients will have to consider financial burden when making decision

Leqembi, a newly approved drug for use in people with mild cognitive impairment or early Alzheimer's disease, comes with a price of $26,500 a year.

Experts say the high price, along with Medicare only covering the drug for patients enrolled in a clinical trial, will mean only a limited number of patients will be able to get the drug when it becomes available.

The University of Cincinnati's Alberto Espay, MD, professor of neurology in the UC College of Medicine, director and endowed chair of the James J. and Joan A. Gardner Family Center for Parkinson’s Disease and Movement Disorders at the UC Gardner Neuroscience Institute and a UC Health physician, told NBC News the price of the drug is "very unfortunate."

Espay said doctors will need to include the financial burden as a possible risk of the drug when discussing its potential benefits of modestly slowing the disease. He is a proponent of an alternative theory that it is the loss of the normal amyloid protein, rather than the build-up of the abnormal amyloid plaques, that leads to degeneration.

Previously, Espay noted the benefits of Leqembi may stem from the fact that it increases levels of the normal protein in the brain in addition to its primary aim of removing plaques.

Read the NBC News article on the price of Leqembi.

Read the NBC News article featuring Espay about unanswered questions about Leqembi.

Espay also discussed Leqembi and the state of Alzheimer's research on WVXU's Cincinnati Edition. Listen to the Cincinnati Edition segment.

Read more about Espay's research and alternative Alzheimer's hypothesis.

Featured photo at top courtesy of Unsplash.

Related Stories

9858 Results
1

President picks exceptional talent

April 28, 2021

The University of Cincinnati 2021 Presidential Leadership Medal of Excellence Awards honor six undergraduate scholars for scholarship, leadership, character, service and the ideals of the university. Awardees are spotlighted for exceptional academics, creativity, community service and innovation.

2

Grad students earn president's highest honor

April 28, 2021

The University of Cincinnati 2021 Presidential Medal of Graduate Student Excellence Awards honor three graduate scholars for scholarship, leadership, character, service and the ideals of the university. Awardees are spotlighted for exceptional academics, creativity, community service and innovation.

4

Finding community and building a future

July 9, 2021

As a University of Cincinnati College of Medicine student, Sarah Appeadu, MD, ’21, remembers journaling on the “3 Cs” that got her through medical school: Community, community, community. Now, when she lists the people who supported her through four years of training—the last year in a global pandemic—it keeps growing: her family, her church, her classmates, and the college’s Office of Student Affairs and Office of Diversity, Equity and Inclusion. “I look back and it was such a crucial time to really be nurtured in that way,” she says. “I’m so thankful that I had those people. It shows being around the right people really mattered. That’s my same hope for residency even.”

8

UC Receives $1.9 Million to Study Pain

February 15, 2016

Jun-Ming Zhang, MD, of the UC College of Medicine, is the principal investigator of a $1.95 million grant to study the interacting roles of the sympathetic and sensory nervous and immune systems in back and neuropathic pain models.

9

MD Magazine: Generic Drug Equally Effective in Epilespy

February 22, 2016

Michael Privitera, MD, a professor of neurology at UC's College of Medicine and director of the Epilepsy Center at the UC Neuroscience Institute, is featured in this story about research he led that examined the efficacy of generic drug substitution for epilepsy.