August 14, 2023
A federally funded study, led by University of Cincinnati researcher Nalinikanth Kotagiri, looks to develop a new imaging method that can identify certain types of lung infections — in real time — in order to speed up treatment for critically ill patients.
November 7, 2022
The University of Cincinnati is part of a multimillion-dollar grant from the National Heart, Lung, and Blood Institute to study a strategy to prevent stroke in patients with atrial fibrillation. The trial will incorporate the use of an app on Apple Watch to monitor an irregular heartbeat to reduce patients’ reliance on blood-thinning medication.
April 22, 2021
Taejeong Song, PhD, a postdoctoral fellow in the UC College of Medicine, says a regulatory protein found in skeletal muscle fiber may play an important role in the body’s fight or flight response when encountering dangerous situations.
May 13, 2021
Donald Lynch Jr., MD, assistant professor at the University of Cincinnati College of Medicine, will be presenting preliminary research at the American College of Cardiology on Saturday, May 15, that suggests plasma proteins discovered in the blood samples of diabetic patients who went on to develop obstructive coronary disease (OCAD) may serve as biomarkers of severe heart blockage.
October 29, 2020
Donald Lynch, MD, a University of Cincinnati cardiologist, is partnering with researchers in St. Louis and rural Georgia to develop a smartphone app that will deliver COVID-19 information and education that is targeted toward Black communities.
June 8, 2023
Each year, about 200,000 people in the United States are diagnosed with a bulge in the lower part of the aorta, the main artery in the body, called an abdominal aortic aneurysm (AAA). New research from the University of Cincinnati examines the role a particular metabolite plays in the development of AAA and could lead to the first treatment of the condition.
March 25, 2021
A team of UC College of Medicine researchers tackled a cardiac condition in Maine Coon cats after a baffled owner reached out for help. Sakthivel Sadayappan, PhD, lead a team that was able to identify a mutation in a gene known as troponin-T (TNNT2), which regulates heart contractility. It is present in humans, but this was the first time it was associated with heart disease in cats.
September 22, 2020
Researchers at the University of Cincinnati and UC Health will host a Phase 2 clinical trial (NCT04511650) to examine the effects of a drug that targets blood vessel inflammation and injury in patients with COVID-19. They will study the effects of razuprotafib, an investigational drug that activates a key pathway for stabilizing blood vessels in the lung and other organs in patients with moderate to severe cases of the respiratory illness caused by the novel coronavirus SARS-CoV-2. The drug may prevent and treat respiratory distress in COVID-19 patients. The Phase 2 clinical trial will assess safety, tolerability and efficacy of razuprotafib.
June 3, 2020
Donald Lynch, MD, will conduct an observational study of 150 heart valve replacement patients at UC Medical Center and the University of Kentucky. These patients will undergo TAVR, a procedure in which a catheter-mounted valve is inserted through a small incision in the groin and is minimally invasive compared to open heart surgery. Patients who consent to participate in the study will have blood drawn before the procedure begins, prior to discharge and during clinic follow-ups to determine what biomarkers are predictive of short- and long-term clinical outcomes.