UC researchers to study presence of MRSA in air in hospital settings

Most MRSA infections occur in people who've been in hospitals or other health care settings, making it a particular risk to those who work in such facilities, and a team of UC researchers has been awarded a $300,000 grant from the Ohio Bureau of Workers’ Compensation to conduct environmental surveillance at University of Cincinnati Medical Center.

MRSA is primarily transmitted through person-to-person contact and contact with contaminated surfaces, but experts have emerging evidence of the presence of MRSA in the air in hospital settings. As of 2021, Ohio had an incidence of MRSA that's greater than the national incidence, according to the state department of health. 

“As we know from COVID-19 research, mere detection of a pathogen doesn't mean it can cause infection,” she said. “The microbe should be live or viable to cause an infection.”

Researchers will also study the effectiveness of the current control measures, which include regular testing of admitted patients, periodic disinfection and high air exchange rates within the hospital. They will also study the effectiveness of alternate methods of inactivating MRSA, such as UVC light sterilizers, disinfectant sprays and air purifiers.

Shankar explained that if researchers discover that MRSA is live, they will follow protocols to disinfect the air and make recommendations to further enhance workplace safety. 

“Our team will also seek input from hospital workers about current protocols and potential changes in the future,” she said. “We expect existing policies to minimize the risk of MRSA exposure to workers and patients. Our study gives an added layer of confidence that the risk of exposure to MRSA is minimal to none in their units.”

One of Shankar’s collaborators explained the significance of how they are conducting their work.

“Understanding this unique environment is key to being able to collect samples and interact with hospital staff,” said Elizabeth Bien, PhD, assistant professor in the College of Nursing. “As a previous infection preventionist and an occupational health nurse who was trained to focus on the worker as a patient, I am excited to partner on this work.”

The study team also includes Jagjit Yadav, PhD, from the Department of Environmental and Public Health Sciences; Vivek Narendran, MD, in the Division of Neonatology in the Department of Pediatrics and a Cincinnati Children’s Hospital physician; and industry collaborator Arantzazu Eiguren-Fernandez, senior research chemist at Aerosol Dynamics Inc.

Featured image at top: A Petri dish with bacteria growing inside. Photo/Provided